2-Chloro-5-nitrobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16588-02-6 |
| Product name | 2-Chloro-5-nitrobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-nitrobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-nitrobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-nitrobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the insecticide flupyradifurone | Produced via multi-step reactions—including cyclization and substitution—with compounds such as methyl 2-amino-3-methylbutyrate |
| Pharmaceuticals | Structural building block for anticancer agents and kinase inhibitors | Used as a multifunctional aromatic substrate (bearing nitro, chloro, or cyano groups) in coupling, reduction, and ammonolysis reactions to construct active molecular scaffolds |
| Dyes | Intermediate for high-performance azo dyes and reactive dyes | Integrated into chromophore systems via diazotization-coupling reactions; alternatively, the cyano group is hydrolyzed to carboxylic acid for modification of dye-fixing functional groups |
Manufacturing Quality Control of 2-Chloro-5-nitrobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., starting materials, isomers, degradation products) using gradient HPLC-UV with a suitable C18 column. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Nitro Group Content | Redox Titration | Potentiometric titration with sodium nitrite in acidic medium to determine nitro group equivalents via diazotization coupling. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values. |
| Bulk Density | ASTM D1895 Method A | Measurement of mass per unit volume for freely settled powder in a standardized cylinder. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and non-targeted screening of residual process-related organics using gas chromatography coupled with mass spectrometry. |
Technical Specifications of 2-Chloro-5-nitrobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 74–78°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-nitrobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-nitrobenzonitrile
Packaging of 2-Chloro-5-nitrobenzonitrile
Industrial 2-Chloro-5-nitrobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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