2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 165904-22-3 |
| Product name | 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key boronate ester intermediate in Suzuki-Miyaura cross-coupling reactions to construct C–C bonds, enabling synthesis of active pharmaceutical ingredients (APIs) containing phenethyl motifs—such as kinase inhibitors and G protein-coupled receptor (GPCR) modulators | Reacted with aryl/heteroaryl halides or pseudohalides (e.g., bromobenzene, 4-chloropyridine) under heating in the presence of a palladium catalyst (e.g., Pd(dppf)Cl₂, Pd(PPh₃)₄), a base (e.g., Na₂CO₃, K₃PO₄), and an organic solvent (e.g., 1,4-dioxane, toluene) |
| Materials Science | Used to incorporate phenethyl-functionalized units into conjugated polymers and hole-transport materials for organic light-emitting diodes (OLEDs) | Participates in multi-step palladium-catalyzed cross-coupling reactions to build π-conjugated backbones, typically copolymerized with monomers such as 2,5-dibromothiophene or 2,7-dibromofluorene |
| Agrochemical R&D | Employed as a structural modification building block to introduce flexible phenethyl side chains, thereby optimizing lipophilicity, target binding affinity, and metabolic stability of candidate molecules | Undergoes Suzuki coupling with heterocyclic halides (e.g., 5-bromopyrimidine, 2-chloro-5-(trifluoromethyl)pyridine) to generate novel insecticidal or fungicidal lead compounds |
Manufacturing Quality Control of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase chromatography with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., residual starting materials, boronic acid, deborylated by-products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, toluene, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical reaction stoichiometry. |
| Residual Boron | ICP-OES | Quantification of total elemental boron after acid digestion by inductively coupled plasma optical emission spectroscopy. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection and quantification of toxic metals after microwave-assisted acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residues after digestion using ICP-MS for high sensitivity and selectivity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Optical Rotation | [a]D Measurement | Determination of specific rotation using sodium D-line light source to assess chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering pattern of laser beam. |
| Bulk Density | USP <616> Tap Density Test | Measurement of mass per unit volume before and after mechanical tapping to assess flowability and packing behavior. |
Technical Specifications of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Colorless solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
Safety Information of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER
Industrial 2-PHENYLETHYL-1-BORONIC ACID PINACOL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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