China Factory Direct
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| CAS number | 16605-99-5 |
| Product name | METHYL BIPHENYL-2-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of angiotensin II receptor blockers (e.g., losartan, irbesartan) | Used to construct the biphenyl tetrazole scaffold via condensation, substitution, or coupling reactions with reagents such as o-phenylenediamine or haloarenes |
| Pesticides | Used in the synthesis of bioactive biphenyl compounds | Applied in transesterification, hydrolysis, or arylation reactions to generate derivatives with herbicidal or fungicidal activity |
| Organic Synthesis | Synthetic building block for constructing complex biphenyl structures | Introduces the carboxylate ester functional group in palladium-catalyzed cross-coupling (e.g., Suzuki reaction) or nucleophilic substitution reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine/methanol medium to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectroscopy with matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography | Separation of chloride ions on an anion-exchange column with conductivity detection, calibrated against sodium chloride standards. |
| Acid Value | Acid-Base Titration | Titration with standardized potassium hydroxide ethanol solution using phenolphthalein indicator to determine free carboxylic acid content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against defined standards under controlled white light and viewing conditions. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to determine inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as function of angle to calculate particle size distribution in dispersed powder sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light passing through a solution to assess chiral purity and identity. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.