5-Fluoro-4-hydrazinyl-2-methoxypyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 166524-64-7 |
| Product name | 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs (e.g., synthesis of EGFR inhibitors and other targeted therapeutics) | Chemical synthesis |
| Pharmaceuticals | Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) | Organic synthesis |
Manufacturing Quality Control of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Chemical Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Using ¹H NMR, ¹³C NMR, and 19F NMR to analyze chemical shifts and coupling patterns of hydrogen, carbon, and fluorine atoms to confirm the target molecular structure. |
| Molecular Weight and Purity | Mass Spectrometry (MS) | Employing ESI-MS or EI-MS to determine the molecular ion peak for molecular weight confirmation; high-resolution mass spectrometry (HRMS) is used to verify elemental composition. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Using reversed-phase C18 columns with UV detection (e.g., 254 nm), quantifying the main component and impurities based on retention time and peak area. |
| Impurity Limit Testing | HPLC-UV / HPLC-DAD | Utilizing diode array detection (DAD) to identify impurity peaks and compare spectral profiles, assessing related substances (such as synthetic by-products and degradation products). |
| Moisture Content | Karl Fischer Titration | Accurately determining water content via titration method to ensure compliance with drying loss or moisture content specifications (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Headspace gas chromatography used to detect residual organic solvents (e.g., methanol, ethanol, DMF), meeting ICH Q3C guidelines. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determining the melting temperature range as a physical constant to assist in assessing purity and crystalline form consistency. |
| Appearance and Physical Characteristics | Visual Inspection and Microscopic Examination | Observing color, crystal morphology, and whether clumping occurs to preliminarily evaluate physical condition against standard criteria. |
| Heavy Metal Residue | ICP-MS or Atomic Absorption Spectroscopy (AAS) | Detecting total or specific heavy metals (e.g., lead, arsenic, cadmium, mercury), complying with pharmacopoeia or ICH Q3D requirements (typically ≤10–20 ppm). |
| Polymorph Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Comparing diffraction patterns with reference standards to ensure consistent polymorphic form across batches, preventing issues related to stability or solubility caused by polymorphic variations. |
Technical Specifications of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
Safety Information of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine
Industrial 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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