China Factory Direct
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| CAS number | 1670-81-1 |
| Product name | Indole-5-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., etoposide derivatives) | Constructing the indole ring side chain via palladium-catalyzed coupling or reductive amination |
| Agrochemicals | Structural building block for plant growth regulators and fungicides | Synthesizing novel agroactive molecules featuring an indole scaffold, such as auxin-like compounds |
| Materials Science | Building block for hole-transport materials in organic light-emitting diodes (OLEDs) | Introducing into conjugated polymer backbones or small-molecule hole-transport layers via bromination, Suzuki coupling, and other modifications |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies indole-5-carboxylic acid concentration using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., indole, isomers, decarboxylated or oxidized by-products) using gradient HPLC-UV with suitable column and mobile phase. |
| Residual Solvents | GC-FID | Determines trace levels of process solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection using headspace sampling. |
| Heavy Metals | ICP-MS | Measures total content of toxic elements (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Water Content | Karl Fischer Titration | Determines trace water by volumetric or coulometric titration with iodine-based reagent, based on the stoichiometric reaction of water with iodine and sulfur dioxide. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid indole-5-carboxylic acid transitions to liquid, indicating purity and crystallinity via thermal behavior. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles or discoloration against established reference standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing of the remaining sulfate-free ash. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection following aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition with sulfuric acid treatment, reflecting total mineral content including sulfates. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to detect chiral impurities or enantiomeric excess, though compound is achiral; used as identity and purity check. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode, indicating residual acidic/basic process residues. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 168–172°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.