China Factory Direct
|
|
| CAS number | 1670-83-3 |
| Product name | 1H-Indole-7-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antitumor agents (e.g., etoposide derivatives) | Prepared via multistep organic synthesis, including Vilsmeier–Haack formylation and oxidation |
| Pesticide R&D | Structural scaffold for designing novel plant growth regulators and insecticides | Serves as a heterocyclic core in coupling reactions or functional group modifications to construct biologically active indole derivatives |
| Organic Synthesis | Chiral ligand or catalyst precursor in high-value fine chemical synthesis | Converted into chiral indole derivatives—used in catalytic system construction—via esterification, reduction, and asymmetric hydrogenation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., indole, 7-hydroxyindole, decarboxylation products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-OES | Multi-element quantitative analysis of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after controlled incineration at 600-700 C followed by weighing of the cooled residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of the bulk material against established reference standards under controlled lighting. |
| Loss on Drying | Thermogravimetric Analysis | Measurement of mass loss upon heating at 105 C for 2 hours, indicating volatile content including residual moisture and low-boiling impurities. |
| Optical Rotation | Polarimetry | Determination of specific rotation using sodium D-line light, reflecting chiral purity and absence of racemization. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 162–166 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.