6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16732-73-3 |
| Product name | 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate for synthesizing biologically active indole derivatives, such as 5-HT3 receptor antagonists or anti-inflammatory agents | Prepared via carboxylation and methoxylation of the indole ring; common synthetic routes include O-methylation of 2-indolecarboxylic acid under basic conditions or regioselective functionalization via transition-metal-catalyzed C–H activation |
| Agrochemicals | Used as a structural building block for synthesizing novel insecticides or fungicides | Indole-containing active molecules are constructed via coupling with acyl chlorides or isocyanates, followed by purification and crystallization to obtain high-purity intermediates |
| Organic Synthesis | Used as a versatile synthetic building block for constructing complex heterocyclic systems | Serves as a key intermediate in multistep syntheses, participating in classical organic transformations including the Bischler–Napieralski reaction, Pictet–Spengler cyclization, and Mannich reaction |
Manufacturing Quality Control of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode array detection; identification and quantification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, DMF) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantitative determination of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-750 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light in solution, indicating chiral purity and identity, per USP <781>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms via filtration, membrane transfer to agar media, and colony counting after incubation per USP <61>. |
Technical Specifications of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
Safety Information of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
Industrial 6-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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