6-Chloroindole-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16732-75-5 |
| Product name | 6-Chloroindole-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Chloroindole-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Chloroindole-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Chloroindole-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., sunitinib analogues) | Used to construct the quinolinone scaffold via multi-step reactions including substitution and cyclization with piperazine derivatives |
| Agrochemicals | Synthesis precursor for novel plant growth regulators and insecticides | Applied in palladium-catalyzed cross-coupling reactions to introduce heteroaryl side chains, enhancing biological activity |
| Organic Synthesis | Building block for indole-based functional materials | Carboxyl group modified via esterification or amidation, followed by metal-catalyzed C–H activation to achieve structural diversification |
Manufacturing Quality Control of 6-Chloroindole-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time and UV response relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., DMF, methanol) using gas chromatography with flame ionization detection. |
| Chloride Content | Ion Chromatography (IC) | Measures inorganic chloride ions via suppressed conductivity detection after anion exchange separation. |
| Heavy Metals | ICP-OES | Determines total elemental metals (e.g., Pb, Cd, Ni) by plasma excitation and atomic emission spectroscopy. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine generated electrochemically in pyridine-methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measures volatile matter loss by weight difference before and after drying under specified temperature and time. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in laser light scattering from dispersed particles in liquid medium. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by detecting rotation angle of plane-polarized light passing through solution at specified concentration and wavelength. |
| Residue on Ignition | Gravimetric (500–600 C) | Quantifies non-volatile inorganic residue after high-temperature ashing and weighing. |
Technical Specifications of 6-Chloroindole-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 215–219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Chloroindole-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Chloroindole-2-carboxylic acid
Safety Information of 6-Chloroindole-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 6-Chloroindole-2-carboxylic acid
Industrial 6-Chloroindole-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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