1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 167423-93-0 |
| Product name | 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Critical chiral intermediate for synthesizing piperidine-containing drug molecules (e.g., JAK inhibitors, NK1 receptor antagonists) | Following chiral resolution or asymmetric synthesis, the target API scaffold is constructed via BOC deprotection, hydrolysis, and coupling steps |
| Organic Synthesis | Protected piperidine carboxylic acid derivative providing a stable, orthogonally removable amino protecting group | The BOC protecting group is selectively removed under acidic conditions (e.g., TFA/DCM); the methyl ester group can be further saponified, reduced, or aminolyzed to introduce diverse functional groups |
| Materials Science | Functionalized polymer monomer precursor for preparing smart, stimuli-responsive polymers with nitrogen-containing heterocyclic side chains | N-BOC-piperidine-2-carboxylic acid methyl ester is incorporated into the polymer backbone or side chains via transesterification or click chemistry; subsequent deprotection generates tertiary amine basic sites |
Manufacturing Quality Control of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient reverse-phase HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, THF, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated in situ via reaction with water in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation of phase change. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (600-750 C) and weighing of residual residue. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against defined standards under controlled lighting and white background. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in a standardized aqueous or aqueous-organic solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using angular scattering pattern of laser light and Mie theory calculation. |
Technical Specifications of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -19.0 deg (c=1, CHCl3) |
| Solubility | Freely soluble in dichloromethane, ethyl acetate, and methanol |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
Safety Information of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE
Industrial 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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