N-Cbz-O-tert-butyl-L-serine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1676-75-1 |
| Product name | N-Cbz-O-tert-butyl-L-serine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Cbz-O-tert-butyl-L-serine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Cbz-O-tert-butyl-L-serine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Cbz-O-tert-butyl-L-serine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key raw material for peptide drug synthesis | Used in solid-phase or solution-phase peptide synthesis as a protected serine monomer to prevent side-chain hydroxyl group side reactions. |
| Pharmaceutical Chemicals | Drug intermediate synthesis | Used to synthesize active pharmaceutical ingredients (APIs) containing serine motifs, particularly for constructing peptide- or peptidomimetic-based scaffolds during novel therapeutic development. |
| Biotechnology | Biochemical reagent | Serves as a site-specific modification reagent in protein engineering and peptide modification studies, introducing serine fragments bearing defined protecting groups. |
Manufacturing Quality Control of N-Cbz-O-tert-butyl-L-serine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection to resolve L- and D-enantiomers. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., ethyl acetate, heptane) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Residual Palladium | ICP-MS | Ultra-trace detection of Pd from catalytic hydrogenation steps via inductively coupled plasma mass spectrometry. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 589 nm to confirm chiral integrity and concentration-dependent specific rotation. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected acid, diastereomers) using gradient HPLC. |
| Residual Chloride | Ion Chromatography | Quantification of chloride ions derived from reagents or solvents using suppressed conductivity detection. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified temperature and vacuum conditions to assess volatile content. |
Technical Specifications of N-Cbz-O-tert-butyl-L-serine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -12.0° to -16.0° (c=1, in 1N HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Cbz-O-tert-butyl-L-serine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Cbz-O-tert-butyl-L-serine
Packaging of N-Cbz-O-tert-butyl-L-serine
Industrial N-Cbz-O-tert-butyl-L-serine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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