Boc-L-aspartic acid 4-tert-butyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1676-90-0 |
| Product name | Boc-L-aspartic acid 4-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Boc-L-aspartic acid 4-tert-butyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-L-aspartic acid 4-tert-butyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-L-aspartic acid 4-tert-butyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Side-chain protecting reagent for aspartic acid in peptide synthesis | Used in solid-phase peptide synthesis (SPPS) to selectively protect the β-carboxyl group of aspartic acid and prevent side reactions; the Boc group is removed under acidic conditions (e.g., TFA/DCM), while the tBu ester is cleaved under strong acidic (e.g., TFA) or basic conditions, enabling orthogonal deprotection |
| Biochemistry | Preparation of structurally defined peptide drug intermediates (e.g., antitumor peptides, hormone analogs) | Serves as a key building block in Fmoc/tBu-based peptide chain elongation, ensuring chemical stability of aspartic acid residues during coupling and deprotection cycles |
| Diagnostics Reagent Development | Synthesis of targeting peptide probes (e.g., radiolabeled peptides) | Maintains aspartic acid side-chain integrity prior to conjugation of fluorescent or chelating groups under mild coupling conditions (e.g., DIC/HOBt), preserving probe specificity and binding activity |
Manufacturing Quality Control of Boc-L-aspartic acid 4-tert-butyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, THF, toluene) by flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration with iodine-based reagent. |
| Optical Rotation | [alpha]D | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metal impurities (e.g., Pb, Cd, Ni, Fe) by plasma excitation and atomic emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection. |
| Residual Palladium | ICP-MS | Detects trace Pd catalyst residues with high sensitivity via inductively coupled plasma mass spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition as identity and purity indicator. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting conditions. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified temperature/vacuum to determine volatile content. |
| pH of Solution | pH Meter | Measures acidity/basicity of aqueous suspension (e.g., 1% w/v) using calibrated electrode. |
Technical Specifications of Boc-L-aspartic acid 4-tert-butyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +1.5 to +2.5 deg (c=1, in DMF) |
| Melting Point | 78 to 82 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Boc-L-aspartic acid 4-tert-butyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-L-aspartic acid 4-tert-butyl ester
Safety Information of Boc-L-aspartic acid 4-tert-butyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Boc-L-aspartic acid 4-tert-butyl ester
Industrial Boc-L-aspartic acid 4-tert-butyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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