China Factory Direct
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| CAS number | 16771-85-0 |
| Product name | 1-(3-Methoxypropyl)piperidin-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing central nervous system (CNS) drugs, including antidepressants and anxiolytics | Used as a key structural unit in multistep organic synthesis; piperidine ring side chains are typically constructed via reductive amination or N-alkylation |
| Pharmaceuticals | Piperidinone structural motif in drug candidate molecules | Introduced during medicinal chemistry structure optimization to improve pharmacokinetic properties—such as metabolic stability and blood-brain barrier permeability |
| Chemicals | Organic synthesis building block for preparing functionalized piperidine derivatives | Subjected to standard organic transformations, including Grignard addition, oximation-reduction, or N-alkylation with alkyl halides |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient HPLC with UV detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using headspace sampling and internal standard calibration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent; water reacts stoichiometrically to generate endpoint current or volume change. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with suppressed conductivity detection; quantified against chloride standard. |
| Residue on Ignition | Gravimetric Analysis | Mass of inorganic residue determined after high-temperature ashing (700-800 C) and cooling in desiccator. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light; indicates enantiomeric composition and chiral purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting and against white/black background. |
| pH of Aqueous Solution | pH Meter | Potentiometric measurement using calibrated glass electrode in a saturated aqueous suspension or dilute solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine size distribution of solid particles in suspension. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.