1-Acetyl-3-indolinone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16800-68-3 |
| Product name | 1-Acetyl-3-indolinone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Acetyl-3-indolinone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Acetyl-3-indolinone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Acetyl-3-indolinone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., sunitinib analogues) | Undergoes palladium-catalyzed cross-coupling with haloarenes under basic conditions to form C–N bonds |
| Organic Synthesis | Precursor for structural modification of oxindole derivatives | Converted into novel bioactive molecules via derivatization reactions such as reductive amination, acylation, or alkylation |
| Agrochemical R&D | Potential structural motif for plant growth regulators or insecticides | Optimized for inhibitory activity against target enzymes (e.g., chitin synthase) by introducing specific substituents |
Manufacturing Quality Control of 1-Acetyl-3-indolinone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; relative retention times and spectral matching support qualification. |
| Residual Solvents | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using headspace sampling and internal standard calibration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectroscopy with matrix-matched calibration standards. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride quantified via external calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using controlled heating and visual observation of sample phase change. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 600-750 C, expressed as percentage of original sample mass. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, used to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size by measuring angular variation in intensity of laser light scattered by dispersed particles in liquid medium. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using filtration, culture on selective media, and colony counting. |
Technical Specifications of 1-Acetyl-3-indolinone
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Acetyl-3-indolinone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Acetyl-3-indolinone
Packaging of 1-Acetyl-3-indolinone
Industrial 1-Acetyl-3-indolinone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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