China Factory Direct
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| CAS number | 168267-99-0 |
| Product name | 3-Fluoro-4-methylphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of fluorinated pharmaceutical intermediates | Used in Suzuki coupling reactions |
| Medical Imaging | Preparation of PET tracer precursors | Applied in cross-coupling reactions involving boronic acids |
| Agrochemicals | Development of fluorinated pesticide active ingredients | Used in Suzuki-Miyaura coupling reactions |
| Materials Science | Preparation of functional polymer monomers | Applied to introduce boron-containing groups via coupling reactions |
| Dyes & Pigments | Synthesis of fluorinated dye intermediates | Applied in boronic esterification or substitution reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., residual starting materials, deboronated by-products, oxidation products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Quantitative analysis of volatile organic solvents (e.g., THF, toluene, methanol) via headspace gas chromatography with flame ionization detection, per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pd, Ni, Pb, Cd) at trace levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Determination of inorganic residue after controlled charring and sulfuric acid treatment followed by high-temperature incineration and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, indicating crystallinity and presence of impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering intensity of laser light, relevant for filtration and formulation performance. |
| Chloride Content | Ion Chromatography (IC) with Conductivity Detection | Quantification of chloride ions (from hydrochloride salts or synthesis residues) via anion-exchange separation and suppressed conductivity detection. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Elemental quantification of total boron after microwave-assisted acid digestion, verifying stoichiometric integrity of the boronic acid functional group. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.