China Factory Direct
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| CAS number | 16830-24-3 |
| Product name | 2-methyl-4-pyridinecarboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antibiotic APIs | Used to synthesize key side chains or structural units of thiazole- or β-lactam-based antibiotics |
| Pharmaceuticals | Intermediate for cardiovascular drugs | Used to synthesize active pharmaceutical ingredients for treating cardiovascular diseases |
| Chemical Synthesis | Organic synthesis building block | Serves as a foundational raw material for constructing complex organic molecules containing pyridine rings |
| Chemical Synthesis | Esterification product/starting material | Produced via esterification of picolinic acid derivatives, or hydrolyzed to 2-methyl-4-pyridinecarboxylic acid |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching with reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, toluene) against calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-methanol buffer; water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-pptr sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection, calibrated against NaCl standards. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or via automated optical detection as solid converts to liquid under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity or enantiomeric excess. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ignition (600-750 C) to determine non-volatile inorganic contaminants. |
| Appearance | Visual Inspection | Assessment of color and clarity of substance in solution or neat form against established visual standards under controlled lighting. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode in a saturated aqueous suspension or dilute solution. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.525–1.535 |
| Relative Density (20°C/25°C) | 1.09–1.11 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.