China Factory Direct
|
|
| CAS number | 16856-18-1 |
| Product name | L-Arginine alpha-ketoglutarate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an amino acid supplement to support liver function, enhance ammonia metabolism, and assist in the management of hepatic encephalopathy | Formulated into intravenous solutions or oral preparations, commonly mixed with glucose or electrolyte solutions |
| Nutritional Supplements | Added to sports nutrition products and dietary supplements to support nitric oxide synthesis, improve blood flow, and aid post-exercise recovery | Dry blending process; co-formulated with other amino acids (e.g., L-ornithine, L-citrulline) into capsules or powder formulations |
| Biotechnology | Used as a component of cell culture media to support growth and protein expression in mammalian cells (e.g., CHO cells) | Dissolved in basal media (e.g., DMEM, RPMI-1640) at defined concentrations (typically 0.1–2 mM), followed by sterile filtration through a 0.22 μm membrane prior to addition |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-arginine-alpha-ketoglutarate content) | Acid-base titration | Quantifies total basic nitrogen groups via standardized HCl titration with methyl red indicator. |
| Loss on drying | Gravimetric analysis | Measures weight loss after drying at 105 C for 2 h to determine volatile content including moisture. |
| Residue on ignition | Gravimetric analysis | Determines inorganic ash content by incineration at 600 C followed by weighing of residual residue. |
| Chloride impurity | Argentometric titration | Measures chloride ions by precipitation titration with silver nitrate using potassium chromate indicator. |
| Sulfate impurity | Barium sulfate gravimetry | Quantifies sulfate as insoluble BaSO4 precipitate formed after addition of barium chloride solution. |
| Heavy metals (as Pb) | Colorimetric limit test with thioacetamide | Forms colored metal-sulfide complexes in acidic medium; compared visually against lead standard. |
| Iron impurity | UV-Vis spectrophotometry | Measures Fe2+ complex with 1,10-phenanthroline at 510 nm using standard calibration curve. |
| Related substances | HPLC with UV detection | Separates and quantifies structural analogs and degradation products using reversed-phase C18 column and UV detection at 210 nm. |
| Optical rotation | Polarimetry | Determines specific rotation using sodium D-line light to confirm chiral purity and identity. |
| pH of aqueous solution | Potentiometric pH measurement | Measures hydrogen ion activity in 1% w/v aqueous solution using calibrated pH electrode. |
| Microbial contamination | Membrane filtration method | Quantifies aerobic mesophilic microorganisms by filtration, membrane transfer to agar, and colony enumeration after incubation. |
| Particle size distribution | Laser diffraction analysis | Measures volume-based particle size distribution in dry powder using scattered laser light intensity patterns. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | -25.0 to -29.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.