China Factory Direct
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| CAS number | 16867-03-1 |
| Product name | 2-Amino-3-hydroxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., kinase inhibitors) | Used as a ligand in coupling reactions (e.g., Suzuki, Buchwald–Hartwig) or as a starting material for constructing pyridine heterocyclic scaffolds |
| Agrochemicals | Nitrogen-containing heterocyclic structural unit in novel insecticides and fungicides | Participates in cyclization, substitution, or oxidation reactions to build biologically active pyridine derivatives |
| Materials Science | Ligand precursor for electron-transport or emissive layers in organic light-emitting diodes (OLEDs) | Coordinates with metals (e.g., Ir, Pt) to form phosphorescent complexes; films are fabricated via coordination polymerization or solution spin-coating |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with the standard spectrum to confirm consistency of characteristic functional group absorption peaks (such as N–H, O–H, C=N, etc.) of 2-amino-3-hydroxypyridine. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use NMR technology to measure chemical shifts, integration areas, and coupling constants of hydrogen atoms in the sample. Compare with theoretical or reference standard spectra to verify structural consistency. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of an appropriate mixture of water and organic solvent (e.g., methanol or acetonitrile). Detect at around 254 nm using a UV detector. Quantify the main component using external or internal standard methods. |
| Related Substances (Impurity) Test | High-Performance Liquid Chromatography (HPLC) | Similar conditions as assay, but with optimized separation parameters to effectively resolve the main peak from potential impurity peaks (e.g., synthesis intermediates, degradation products). Impurity levels are evaluated using area normalization or standard self-comparison methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved. Calculate the percentage weight loss to control the content of moisture and volatile substances. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ignition Method | After charring the sample, ignite it in a high-temperature furnace at 700–800°C until constant weight. Measure the weight of the residual inorganic matter to control the total amount of inorganic impurities (e.g., metal salts). |
| Heavy Metals | Thioacetamide Method (Colorimetric) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | The traditional method uses thioacetamide to generate hydrogen sulfide under acidic conditions, which reacts with heavy metal ions to form colored precipitates for colorimetric analysis. The modern method employs ICP-MS for highly sensitive quantification of trace heavy metal elements (e.g., Pb, As, Cd, Hg). |
| pH Value | pH Meter Method | Prepare an aqueous solution of a specific concentration (e.g., 1% w/v) and directly measure its pH using a calibrated pH meter to assess the presence of acidic or basic impurities. |
| Melting Point | Capillary Melting Point Method | Using a melting point apparatus or Thiele tube, observe the temperature range from initial melting to complete melting of the sample during heating. This serves as an auxiliary indicator for purity and identity confirmation. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 112–116 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.