2-HYDROXY-4-IODOBENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16870-28-3 |
| Product name | 2-HYDROXY-4-IODOBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-HYDROXY-4-IODOBENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-HYDROXY-4-IODOBENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-HYDROXY-4-IODOBENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing thyroid hormone drugs | Serves as an iodine source and aromatic ring building block in coupling reactions to prepare drugs such as levothyroxine |
| Pharmaceuticals | Precursor for radiolabeled compounds | Enables incorporation of radioactive iodine isotopes (e.g., I-123, I-131) via isotopic exchange or electrophilic substitution for synthesis of diagnostic or therapeutic imaging agents |
| Fine Chemicals | Organic synthesis intermediate | Used in Suzuki coupling, Ullmann reactions, and other transformations to construct C–C or C–N bonds for functional aromatic compounds |
| Materials Science | Raw material for liquid crystal or functional material synthesis | Acts as an iodine-containing functional group building block to introduce high polarity or heavy-atom effects, thereby tuning optoelectronic properties of materials |
Manufacturing Quality Control of 2-HYDROXY-4-IODOBENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic dilution or external calibration. |
| Iodine Content | Potentiometric Titration with AgNO3 | Direct titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection corresponding to AgI precipitation. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time, indicating volatile content including residual moisture and low-boiling impurities. |
| Residue on Ignition | Sulfated Ash Gravimetry | Weight of inorganic residue after high-temperature incineration following sulfuric acid treatment, indicating non-volatile inorganic impurities. |
| pH of Aqueous Suspension | pH Meter Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic character and potential hydrolysis. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs, indicating crystallinity and purity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with KF reagent to quantify trace water based on stoichiometric iodine consumption in pyridine-methanol medium. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to determine volume-based particle size distribution in dispersed dry or wet sample. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
Technical Specifications of 2-HYDROXY-4-IODOBENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 202–206 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-HYDROXY-4-IODOBENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-HYDROXY-4-IODOBENZOIC ACID
Packaging of 2-HYDROXY-4-IODOBENZOIC ACID
Industrial 2-HYDROXY-4-IODOBENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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