China Factory Direct
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| CAS number | 168960-19-8 |
| Product name | (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for antiviral drugs (e.g., oseltamivir) | Applied in asymmetric synthesis or chiral construction steps of multi-step organic synthesis, including cycloaddition and reductive amination reactions |
| Pharmaceutical R&D | Structural modification and structure–activity relationship (SAR) studies of novel neuraminidase inhibitors | Used as a starting material or intermediate for structural derivatization and activity screening at laboratory scale |
| Test Item | Commonly Used Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with reference spectra to confirm the presence of characteristic functional groups (e.g., N–H, O–H, C=C). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyzes the chemical shifts, coupling constants, and integration areas of hydrogen atoms in the compound using ¹H NMR to verify structural and stereochemical features. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employs reversed-phase HPLC with a C18 column and UV detection (typically at 210–230 nm) to quantify the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Uses gradient or isocratic elution to separate and detect process impurities and degradation products; impurity levels are calculated using area normalization or relative response factor methods. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used with a capillary column and FID detector to determine residual organic solvents (e.g., methanol, ethanol, dichloromethane) in accordance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Determines the water content using volumetric or coulometric methods; suitable for salts with crystallization water or hygroscopic hydrochlorides. |
| Melting Point | Melting Point Determination | Measures the temperature range from initial melting to complete melting using a melting point apparatus, serving as an auxiliary indicator of purity and crystal form. |
| Specific Optical Rotation | Polarimetry | Measures the optical rotation of the solution at a specified wavelength (usually the sodium D line, 589 nm) and temperature to confirm the optical purity of the (1S,4R) stereochemistry. |
| pH Value | pH Meter Method | Prepares a solution of defined concentration and measures its pH using a calibrated pH meter to evaluate the acid-base properties and possible residual free base in the hydrochloride salt. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample preparation according to pharmacopoeia general chapters, determines residual heavy metal elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with specified limits. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Weight Method | Dries the sample at a specified temperature (e.g., 105°C) until constant weight to measure the loss of volatile substances (including moisture and some solvents). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178~182°C |
| Optical Rotation | -32.0 ~ -26.0 deg (c=1, H2O) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.