China Factory Direct
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| CAS number | 16937-99-8 |
| Product name | BOC-D-Leucine monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in peptide synthesis as a protected amino acid intermediate | Applied in solid-phase and liquid-phase peptide synthesis |
| Biotechnology | Used as a reagent for protein structural modification | Applied in chemical modification and labeling |
| Pharmaceutical R&D | Used to prepare active pharmaceutical ingredients (APIs) for anticancer or antiviral drugs | Applied in organic synthesis and purification |
| Chemical Research | Used in chiral compound synthesis or asymmetric catalytic reactions | Applied in catalytic reactions and separation/purification |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratios. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based solvent system. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., ethyl acetate, toluene). |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous solution after sample dissolution and filtration. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600-700 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution to confirm chiral integrity and concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine volume-based particle size distribution in dry or slurry form. |
| Microbial Contamination | Membrane Filtration | Filtration of dissolved sample followed by incubation on nutrient agar plates to enumerate aerobic microorganisms. |
| Related Substances | HPLC-DAD | Detection and relative quantification of structurally related impurities using diode array detection across multiple wavelengths. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using a calibrated glass electrode and reference electrode. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 132.0 to 136.0 °C |
| Optical Rotation | +22.0 to +28.0 ° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.