China Factory Direct
|
|
| CAS number | 16947-89-0 |
| Product name | ALPHA-BOC-GAMMA-Z-(DL)-DIAMINOBUTYRIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Bis-protecting reagent for L-2,4-diaminobutyric acid (Dab) residues in peptide synthesis, enabling selective protection of the side-chain amino group and the backbone amino group | Used as a controlled coupling precursor in solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis; the α-amino group is protected with tert-butoxycarbonyl (Boc), the δ-amino group on the side chain is protected with benzyloxycarbonyl (Cbz), and the compound is supplied as a dicyclohexylamine salt to enhance crystallinity and handling stability |
| Organic Synthesis | Building block for drug intermediates containing diamino structural motifs (e.g., antimicrobial peptide mimetics, targeted conjugation molecules) | Orthogonal deprotection: Boc group is removed under acidic conditions (e.g., TFA) to enable backbone elongation, followed by hydrogenolysis to remove the Cbz group |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by gradient HPLC-UV; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Residual Palladium | ICP-OES | Quantification of Pd after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution after sample dissolution and filtration. |
| Optical Rotation | [alpha]D | Measurement of specific rotation using sodium D-line light source in a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing to assess inorganic impurities and catalyst residues. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) to verify acid-base character consistent with salt form. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 147°C |
| Optical Rotation | +12.5° to +14.5° (c=1, in DMF) |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.