1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 170017-73-9 |
| Product name | 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate for synthesizing biologically active piperazine compounds | Boc protection of the amino group of 4-(2-nitrophenyl)piperazine enhances stability and reaction selectivity, enabling subsequent construction of complex drug molecules |
| Organic Synthesis | Used to synthesize novel functionalized piperazine derivatives for advanced material and catalyst design | Boc group introduction and removal are carried out via standard organic synthesis methods—such as nucleophilic substitution and coupling reactions—in specified solvents to construct the target product |
Manufacturing Quality Control of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, THF, ethyl acetate) by headspace GC with flame ionization detection using calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically or added stoichiometrically in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution calibration. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection and external calibration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after charring and incineration at 700-800 C, followed by precise weighing of the cooled crucible. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light (589 nm) to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Evaluates acidity/basicity by measuring hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size by measuring angular variation in intensity of laser light scattered by dispersed sample in liquid medium. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation per pharmacopeial guidelines. |
Technical Specifications of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 45–49°C |
| Solubility | Soluble in dichloromethane, DMF, and acetonitrile; slightly soluble in water |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
Safety Information of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE
Industrial 1-TERT-BUTOXYCARBONYL-4-(2-NITROPHENYL)PIPERAZINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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