China Factory Direct
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| CAS number | 170886-13-2 |
| Product name | 2-(TRIFLUOROMETHYL)-4-HYDROXYPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of pesticide intermediates | Prepared via organic synthesis methods, including nucleophilic substitution and redox reactions |
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used to introduce functional groups into drug molecules through multistep organic synthesis |
| High-performance polymers | Functional additives | Applied as polymer modifiers, incorporated into materials via copolymerization or grafting reactions |
| Analytical Test Item | Common Analytical Methods | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column with methanol/water or acetonitrile/buffer salt as the mobile phase, and UV detector (e.g., 254 nm) for quantification of the main component's purity, assessing impurity content. |
| Related Substances/Impurities Analysis | HPLC or UPLC | Gradient elution is used to separate potential process-related impurities or degradation products. LC-MS is employed for structural identification, in compliance with ICH Q3A/B requirements. |
| Moisture Determination | Karl Fischer Titration | Determines trace moisture content in the sample using potentiometric or volumetric titration, ensuring it meets the specified limits for loss on drying or moisture content (e.g., ≤0.5%). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | After heating the sample to equilibrate, residual organic solvents (e.g., methanol, ethyl acetate) are detected by GC-FID or MS, in compliance with ICH Q3C limits. |
| Heavy Metal Testing | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After digestion, heavy metals such as lead, cadmium, mercury, and arsenic are detected, in compliance with ICH Q3D guidelines for elemental impurities. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | ¹H-NMR and ¹³C-NMR confirm molecular skeleton and substituent positions; IR verifies functional groups (e.g., -OH, C-F); MS determines molecular weight and fragmentation patterns. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determines the melting temperature range of the compound, serving as a physical constant reference to assess crystalline form consistency and purity. |
| pH Value/Acid-Base Properties | pH Meter Measurement (in aqueous solution or appropriate solvent) | Prepare a solution of a certain concentration and measure its pH value, evaluating its acidic or basic properties to ensure they meet quality standards (e.g., 4-hydroxypyridine has weak acidity). |
| Loss on Drying | Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, calculating the percentage of weight loss to reflect volatile substances or adsorbed water content. |
| Crystalline Form Analysis | X-ray Powder Diffraction (XRPD) | Analyze characteristic diffraction peaks to confirm the crystal structure, identifying the presence of polymorphic forms and ensuring crystalline form consistency and stability across batches. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.