4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 171745-13-4 |
| Product name | 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Experimental anticancer drug candidate targeting EGFR and VEGFR-2 kinases | Used as a lead compound for structural optimization and structure–activity relationship (SAR) studies in in vitro kinase inhibition assays and cell proliferation inhibition assays |
| Pharmaceutical R&D | Anti-angiogenesis research tool compound | Applied in HUVEC (human umbilical vein endothelial cell) tube formation assays and the chick chorioallantoic membrane (CAM) angiogenesis inhibition model |
| Pharmaceutical R&D | Multi-target kinase inhibitor chemical probe | Employed to validate potential inhibitory activity against kinases such as BRAF and PDGFRβ via molecular docking simulations and kinase profiling assays (e.g., KinaseProfiler™) |
Manufacturing Quality Control of 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength, comparing peak area to reference standard. |
| Related Substances | HPLC-DAD | Detects and quantifies structurally related impurities using diode-array detection for spectral confirmation and peak purity assessment. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration using iodine-based reagent where water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) by inductively coupled plasma mass spectrometry after acid digestion and matrix separation. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange column separation. |
| Residual Palladium | ICP-OES | Measures palladium from catalytic hydrogenation residues by inductively coupled plasma optical emission spectroscopy following microwave digestion. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measures volatile matter loss by weight difference before and after controlled heating under specified conditions. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral centers in solution, indicating enantiomeric identity and purity. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension by analyzing angular variation in laser light scattering intensity. |
| Microbial Limits | Membrane Filtration and Culture | Detects aerobic microorganisms and specified pathogens by filtration, membrane transfer to selective media, and colony enumeration after incubation. |
Technical Specifications of 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 218-222°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
Industrial 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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