China Factory Direct
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| CAS number | 17199-29-0 |
| Product name | (S)-(+)-Mandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Production of antibiotics, antiviral agents, etc. | Prepared via microbial fermentation or chemical synthesis |
| Agrochemical Intermediates | Manufacture of herbicides, insecticides, etc. | Converted into corresponding active agrochemical ingredients via chemical reactions |
| Organic Synthesis | Synthesis of other chemicals | Used as a chiral source or reactant in various organic reactions |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase chromatographic column with a mobile phase of methanol-water or buffer solution (e.g., phosphate buffer), detected by a UV detector (approximately 210–254 nm). Quantification is performed using external or internal standard methods to determine mandelic acid content, offering high sensitivity and resolution. |
| Purity Analysis | Gas Chromatography (GC) | Applicable for detecting volatile derivatives. Mandelic acid must first be derivatized (e.g., esterified) prior to injection. Separation is achieved using a capillary column with FID detection to identify and quantify impurity peaks, suitable for analyzing residual organic solvents and volatile impurities. |
| Water Content | Karl Fischer Titration | Based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment, this method precisely measures water content in samples, ideal for controlling trace moisture in active pharmaceutical ingredients. |
| Related Substances (Impurities) | HPLC Method | Similar to content assay, but employs gradient elution to better separate the main peak from impurity peaks. Detects and quantifies synthesis intermediates, degradation products, and other related substances; typically requires total impurities to be below specified limits. |
| Acid Value / Neutralization Equivalent | Acid-Base Titration | Titrates a mandelic acid solution with standardized sodium hydroxide solution, using phenolphthalein or potentiometric methods to indicate the endpoint. Calculates acid value or neutralization equivalent to verify the functional group content meets specifications. |
| Melting Point | Melting Point Determination | Uses a melting point apparatus or capillary method to measure the melting temperature of mandelic acid (literature value: approximately 118–120°C). Used for preliminary identification and purity assessment; a narrow melting range indicates high purity. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, residual heavy metal elements such as lead, arsenic, and mercury are measured to ensure compliance with pharmacopeial or safety standards for pharmaceuticals, food, or cosmetics. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, headspace-GC is used to detect residual organic solvents (e.g., methanol, ethanol, acetone) from the manufacturing process, with FID detection, ensuring compliance with specified limits. |
| Polymorph Analysis | X-Ray Powder Diffraction (XRD) | Analyzes the crystal structure of mandelic acid to confirm polymorphic consistency, preventing potential impacts on solubility and stability due to different crystal forms. |
| Infrared Spectroscopy Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Sample is analyzed via pellet or ATR method to obtain an infrared absorption spectrum, which is compared with a reference spectrum to confirm characteristic molecular peaks (e.g., carboxyl, aromatic ring, hydroxyl groups) for qualitative identification. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 117.0 to 121.0 °C |
| Optical Rotation | +150.0 to +157.0° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.