China Factory Direct
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| CAS number | 17201-43-3 |
| Product name | 4-Cyanobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of drug molecules, including kinase inhibitors, antitumor compounds, and cardiovascular agents | Introduces a cyanobenzyl moiety via nucleophilic substitution in organic synthesis, commonly employed to construct pharmacologically active scaffolds |
| Agrochemicals | Used as an intermediate in the preparation of herbicides, insecticides, and fungicides—e.g., benzoylurea insecticides | Undergoes functional group transformations to further derivatize the cyano and bromo groups into bioactive agrochemical ingredients |
| Materials Science | Used as a monomer or modifier in the synthesis of high-performance polymers, such as polyimides and liquid crystal polymers | Incorporates cyano functionality via polymerization or crosslinking reactions to enhance thermal stability and mechanical properties |
| Fine Chemicals | Used in the synthesis of dyes, optical brighteners, and photoinitiators | Serves as an aromatic building block; the electronic effect of the cyano group modulates molecular luminescence or reactivity |
| Research Reagents | Used as a functionalized benzyl reagent for constructing complex molecules in organic synthesis | Commonly applied in Suzuki coupling, nucleophilic substitution, and other reactions to introduce the cyanobenzyl functional group |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance and Physical Characteristics | Visual Inspection + Physical Property Determination | Observe sample color and state (typically colorless to light yellow crystals or powder), determine melting point (literature value: ~58–62°C), and assess compliance with specifications. |
| Assay | Gas Chromatography (GC) | Separation using a capillary column (e.g., DB-5 or HP-5), quantification with FID detector; concentration of the main component calculated by internal or external standard method, achieving accuracy above 99%. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column with mobile phase of methanol/water or acetonitrile/water; detection by UV detector at 220–254 nm; suitable for quantitative analysis of thermally unstable samples. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Qualitative and semi-quantitative analysis of organic impurities (e.g., unreacted 4-bromotoluene, 4-cyanotoluene, dibrominated by-products); provides structural confirmation. |
| Impurity Analysis | High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Detects polar or thermally labile impurities (e.g., hydrolysis products, oxidized species); offers high sensitivity and structural information, suitable for trace-level impurity control. |
| Bromine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | Sample is combusted in an oxygen bomb to convert bromine into bromide ions (Br⁻), which are then quantified via ion chromatography to verify bromine content against theoretical value (theoretical Br: 44.8%). |
| Moisture Content | Karl Fischer Titration | Use coulometric or volumetric method to determine trace moisture levels; control moisture content ≤0.5% to prevent hydrolysis or stability issues during storage. |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Detect organic solvents possibly remaining from manufacturing (e.g., toluene, acetonitrile, DMF); controlled according to ICH Q3C guideline limits. |
| Melting Point | Capillary Melting Point Apparatus | Precisely measure melting range (58–62°C); used as a preliminary indicator of purity—broad melting range suggests presence of impurities. |
| UV Absorption Spectrum | UV-Visible Spectrophotometer (UV-Vis) | Measure characteristic absorption peaks (λmax ≈ 250–260 nm) in ethanol or acetonitrile; useful for identification and quantitative analysis (with calibration curve). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) | Determine residual heavy metals such as lead, cadmium, mercury, and arsenic; meet pharmaceutical or electronic-grade material standards (e.g., ≤10 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.