3-Hydroxy-cyclobutanecarboxylic acid ethyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 17205-02-6 |
| Product name | 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for synthesizing antiviral drugs (e.g., HCV NS5A inhibitors) | Core molecular structure assembled via hydrolysis, amidation, and other steps following chiral resolution or asymmetric synthesis |
| Organic Synthesis | Ring-butyl structural unit incorporated into complex molecules to construct biologically active compounds containing four-membered rings | Converted to the corresponding carboxylic acid via ester hydrolysis, or further derivatized via reduction, substitution, and related reactions |
| New Materials Development | Cyclobutane-based precursor explored for liquid crystal materials or polymer monomers | Serves as the synthetic starting point for functionalized cyclobutane monomers in controlled polymerization reactions |
Manufacturing Quality Control of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas to qualified reference standards or threshold responses. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, ethyl acetate) using gas chromatography with flame ionization detection and external calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated electrochemically or added reagent reacting stoichiometrically with water. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric identity. |
| Acid Value | Acid-Base Titration | Neutralizes free carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by incinerating sample at 600-700 C and weighing residual non-volatile matter. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection and external calibration. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of liquid sample against standard references under controlled lighting conditions. |
| Density | Digital Density Meter | Determines mass per unit volume at specified temperature (e.g., 20 C) using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measures light bending angle at air-sample interface using calibrated refractometer at 20 C and sodium D-line wavelength. |
Technical Specifications of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.430–1.440 |
| Optical Rotation | +12.0° to +14.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
Safety Information of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
Industrial 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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