China Factory Direct
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| CAS number | 1722-12-9 |
| Product name | 2-Chloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing herbicides and fungicides | Preparation of pyrimidine derivatives via chlorination, cyclization, and related reactions |
| Pharmaceutical Synthesis | Critical intermediate for antiviral and anticancer drugs | Used to construct biologically active molecular frameworks containing pyrimidine rings, such as nucleoside drug precursors |
| Polymers & Materials | Precursor for functional monomers or crosslinking agents | Introduction of chlorine atoms during polymerization to tailor material properties |
| Dyes & Pigments | Intermediate for synthesizing specific dye compounds | Introduction of pyrimidine structures via electrophilic substitution or coupling reactions |
| Organic Synthesis | General-purpose organic synthesis intermediate for constructing complex molecular scaffolds | Commonly employed in nucleophilic substitution and metal-catalyzed coupling reaction pathways |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (liquid or solid), clarity and transparency to determine the presence of impurities or foreign matter. |
| Assay | Gas Chromatography (GC) | Separation using a capillary column with flame ionization detection (FID); quantify main component concentration via external or internal standard method. |
| High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with UV detection (approx. 254 nm), and methanol-water or acetonitrile-water as mobile phase for separation and quantification. | |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Combines GC separation with MS structural identification capabilities for qualitative and semi-quantitative analysis of impurities. |
| Liquid Chromatography-Mass Spectrometry (LC-MS) | Suitable for detecting thermally unstable or non-volatile impurities; enables precise identification of impurity structures and purity assessment. | |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric method for accurate determination of trace water content, applicable to organic solvent-based compounds. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects organic solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, acetone, dichloromethane) in accordance with ICH guidelines. |
| pH Value (in solution) | pH Meter Method | Dissolve the sample in a suitable solvent (e.g., water or dilute ethanol) and measure acidity/alkalinity using a calibrated pH meter. |
| Melting Point / Boiling Point | Melting Point Apparatus or Boiling Point Determination | Used to assist in purity evaluation when solid impurities are present; 2-chloropyrimidine is a liquid, so boiling point or refractive index is typically measured as a physical constant reference. |
| Refractive Index | Refractometry | Measure refractive index (n20D) at a specified temperature (e.g., 20°C) for identification and preliminary purity screening. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine residual levels of heavy metals such as lead, cadmium, and mercury to meet pharmacopoeial or relevant quality standards. |
| Chloride Impurities | Ion Chromatography (IC) or Titration | Detect free chloride ions or other inorganic chlorine impurities to ensure effective control of by-products from the synthesis process. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 46–49°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.