China Factory Direct
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| CAS number | 17231-51-5 |
| Product name | 3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate in the synthesis of pyrazinamide-class anti-tuberculosis drugs (e.g., pyrazinamide) | Serves as a starting material or key intermediate; the pyrazinamide scaffold is constructed via hydrolysis, amination, and related reactions |
| Pharmaceutical Chemicals | Intermediate in the development of novel antibacterial and antiviral agents | Leverages the compound’s multiple reactive sites—amine, cyano, and bromo groups—for coupling reactions (e.g., Suzuki coupling) or heterocycle modification to build drug candidate libraries |
| Organic Synthesis | Building block for complex pyrazine-containing organic molecules | Functions as a multifunctional pyrazine derivative in nucleophilic substitution, cyclization, and functional group transformation reactions to synthesize biologically active heterocyclic compounds |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., starting materials, intermediates, degradation products) using gradient HPLC/UPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, acetone, methanol) based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Inorganic Residues (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 600–750 °C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of elemental impurities (e.g., Pb, Cd, Ni, Cu) after microwave-assisted acid digestion, using mass spectrometry or optical emission detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and presence of impurities. |
| Residual Bromine (as Br⁻) | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of bromide ion in aqueous extract using anion-exchange column and conductivity detection. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder via light scattering to determine D10, D50, D90 values per USP <429>. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.