1-N-Cbz-4-N-(Boc-aminomethyl)piperidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 172348-56-0 |
| Product name | 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used as a key intermediate in the synthesis of peptide- or protein-based drugs to construct biologically active molecular scaffolds |
| Pharmaceuticals | Anticancer drug development | Applied in the synthesis of antitumor active compounds, providing an aminomethylpiperidine moiety for structural modification |
| Pharmaceuticals | Neurological drug development | Used to synthesize neurotransmitter receptor modulators, including GABA and glutamate receptor-related compounds |
| Pharmaceuticals | Antiviral drug intermediates | Incorporated as a structural unit into antiviral compounds to enhance drug selectivity and stability |
| Biochemistry | Protecting reagent for peptide synthesis | Employed with Cbz and Boc dual protecting groups in selective deprotection strategies to control reaction sequence in solid-phase or solution-phase peptide synthesis |
| Chemical Research | Heterocyclic compound library construction | Serves as a template for constructing structurally diverse piperidine-containing heterocyclic compound libraries for high-throughput screening |
| Chemical Industry | Organic synthesis reagent | Applied as a versatile piperidine derivative in organic synthesis, participating in various coupling, alkylation, and acylation reactions |
Manufacturing Quality Control of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm based on peak area response against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification supported by retention time matching and spiked experiments. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., MeOH, EtOAc, DCM) by headspace GC with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residual Palladium | ICP-MS | Specific quantification of Pd from Cbz deprotection catalyst residue using ICP-MS with palladium-105 or -106 isotope monitoring. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under controlled vacuum and temperature to assess volatile and moisture content. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established reference standards under controlled lighting. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized aqueous or aqueous-organic solution using calibrated pH electrode. |
Technical Specifications of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
Safety Information of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine
Industrial 1-N-Cbz-4-N-(Boc-aminomethyl)piperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply