3-Bromo-2-fluoro-5-methylpyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 17282-01-8 |
| Product name | 3-Bromo-2-fluoro-5-methylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Bromo-2-fluoro-5-methylpyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Bromo-2-fluoro-5-methylpyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Bromo-2-fluoro-5-methylpyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate for antifungal agents (e.g., isavuconazole) | Constructing azole side chains via Suzuki coupling, or introducing imidazole/triazole moieties through nucleophilic substitution |
| Agrochemicals | Intermediate for fungicides | Serving as a pyridine ring scaffold unit, synthesized into active molecules via C–N coupling or functional group transformations |
| Organic Synthesis | Building block for complex molecules containing pyridine rings | Structural modification leveraging differential reactivity of fluorine and bromine atoms (e.g., bromo sites for coupling reactions; fluoro sites for nucleophilic substitution) |
Manufacturing Quality Control of 3-Bromo-2-fluoro-5-methylpyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination by comparison of peak area against a certified reference standard using gas chromatography with flame ionization detection or mass spectrometry. |
| Related Substances | GC-MS or HPLC-DAD | Separation and identification of impurities based on retention time and spectral match; quantification via external standard or area normalization. |
| Residual Solvents | GC-FID with headspace sampling | Volatile organic solvents are extracted in headspace vial and quantified by calibrated GC-FID response. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generated electrochemically or added reagent to react stoichiometrically with water. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection after acid digestion by measuring metal ion mass-to-charge ratios with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of anions on ion-exchange column followed by conductivity detection; quantification using chloride standard calibration. |
| Bromide Impurity | IC or Potentiometric Titration | Anion separation and detection by conductivity (IC) or argentometric titration with silver nitrate endpoint detection. |
| Residual Catalyst (Pd) | ICP-OES | After microwave-assisted acid digestion, palladium is quantified by atomic emission at characteristic wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, observed visually under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against standard reference under controlled lighting and conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Loss on Drying | Gravimetric Analysis (Thermogravimetry) | Mass loss measured after drying under defined temperature, vacuum, and time; reflects volatile and moisture content. |
Technical Specifications of 3-Bromo-2-fluoro-5-methylpyridine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Bromo-2-fluoro-5-methylpyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Bromo-2-fluoro-5-methylpyridine
Safety Information of 3-Bromo-2-fluoro-5-methylpyridine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-Bromo-2-fluoro-5-methylpyridine
Industrial 3-Bromo-2-fluoro-5-methylpyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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