China Factory Direct
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| CAS number | 172900-74-2 |
| Product name | 4-Methoxy-3-(3-methoxypropoxy)benzenemethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for Boehringer Ingelheim’s antidiabetic drug empagliflozin | Serves as a key structural unit: oxidized to generate the intermediate aldehyde, or brominated to produce the benzylic bromide intermediate, enabling construction of the SGLT-2 inhibitor core scaffold |
| Pharmaceutical Industry | Generic intermediate for SGLT-2 inhibitor antidiabetic agents | Used in synthesizing drug molecules featuring a dibenzyl backbone; participates in glycosidic bond formation or carbon–carbon coupling reactions |
| Organic Synthesis | Functional group transformation and modification of alcohols | Bromination at the benzylic position to yield benzylic bromide derivatives, or oxidation to produce corresponding benzaldehyde derivatives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient reverse-phase HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, THF, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion-exchange chromatography. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion and sulfuric acid treatment, followed by high-temperature ignition and weighing. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compound using sodium D-line light in a temperature-controlled cell to confirm stereochemical integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of substance against standard white background under controlled lighting per Ph. Eur. 2.2.1. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode system per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using Mie scattering theory and laser diffraction instrumentation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.