China Factory Direct
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| CAS number | 173140-90-4 |
| Product name | 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used as intermediates in the synthesis of antitumor, antiviral, or other biologically active compounds; employed in organic synthesis steps including epoxidation and nucleophilic substitution reactions. |
| Chemical Synthesis | Organic Synthesis Reagent | Applied as a structural unit of quinolinone derivatives in transition-metal-catalyzed coupling reactions or nucleophilic addition reactions to construct complex molecular frameworks. |
| Materials Science | Functional Materials Research | Potentially used in the synthesis of optoelectronic or biomaterials; serves as a quinoline derivative to impart specific electronic or optical properties. |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with reference spectra to confirm consistency in characteristic functional group absorption peaks (e.g., epoxy group, quinolone ring, benzyloxy group). |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze chemical shifts, coupling constants, and integration areas in proton and carbon spectra to confirm molecular structure and stereochemistry (especially the 2R configuration). | |
| Mass Spectrometry (MS, e.g., ESI-MS or HRMS) | Determine the molecular ion peak to confirm molecular weight and verify structure through fragment ions; high-resolution MS can accurately determine molecular formula. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and a UV detector (based on maximum absorption wavelength, ~254–280 nm); calculate the main component content using external standard or normalization method. |
| Impurity Testing | HPLC Method | Same as above; separate related substances via gradient elution and detect and quantify impurities (e.g., degradation products, isomers, residual starting materials). |
| Gas Chromatography (GC) | If the sample is sufficiently volatile, GC can be used to detect residual solvents (e.g., methanol, ethanol, dichloromethane). | |
| Water Content | Karl Fischer Titration | Precisely determine the water content in the sample; suitable for quality control of active pharmaceutical ingredients (APIs). |
| Residual Solvents | GC Method (Head-space Injection) | According to ICH Q3C guidelines, detect residual organic solvents used during manufacturing to ensure compliance with safety limits. |
| Melting Point | Capillary Melting Point Method | Determine the initial and final melting temperatures using a melting point apparatus; used for identification and purity assessment. |
| Specific Optical Rotation | Polarimetry | Measure the specific optical rotation at a specific wavelength (e.g., sodium D-line, 589 nm) to confirm optical activity and the purity of the (R)-configuration. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Analyze characteristic peaks of solid crystal forms to detect polymorphism and ensure batch-to-batch consistency. |
| Differential Scanning Calorimetry (DSC) | Measure thermal events such as melting endotherms and glass transition temperatures to assist in assessing crystallinity and purity. | |
| Particle Size Distribution | Laser Particle Size Analysis | For raw materials used in solid dosage forms, measure the particle size distribution which affects dissolution and bioavailability. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -18.5 to -16.5° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.