3,4-Dihydroxybenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 17345-61-8 |
| Product name | 3,4-Dihydroxybenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,4-Dihydroxybenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,4-Dihydroxybenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,4-Dihydroxybenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of α-adrenergic agonists (e.g., midodrine) | Organic synthesis |
| Pharmaceuticals | Precursor in the synthesis of 3,4-dihydroxybenzaldehyde (protocatechualdehyde) | Hydrolysis |
| Chemicals | Synthesis of other fine chemicals and organic intermediates | Coupling and substitution reactions |
Manufacturing Quality Control of 3,4-Dihydroxybenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 280 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., 3-hydroxybenzonitrile, catechol, benzonitrile) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions following sample dissolution and dilution. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity consistency. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying sample at 105 C for 2 hours, reflecting volatile content including moisture and solvents. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder via laser scattering to determine D10, D50, D90 values relevant to handling and formulation performance. |
Technical Specifications of 3,4-Dihydroxybenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,4-Dihydroxybenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,4-Dihydroxybenzonitrile
Packaging of 3,4-Dihydroxybenzonitrile
Industrial 3,4-Dihydroxybenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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