(R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 173774-48-6 |
| Product name | (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of chiral drug intermediates | Used as a chiral building block to construct piperazine-containing active pharmaceutical ingredients; participates in coupling reactions or undergoes deprotection followed by further functionalization |
| Organic Synthesis | Synthon in protecting group strategies | The BOC-protected amino group provides selective reaction sites in multistep syntheses; the (R)-configuration enables stereochemical control |
| Biopharmaceutical R&D | Construction of high-throughput screening compound libraries | Applied to synthesize candidate molecules with defined stereochemistry, supporting drug discovery workflows |
Manufacturing Quality Control of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to reference standard. |
| Chiral Purity | Chiral HPLC | Separates enantiomers on a chiral stationary phase and quantifies (R)-enantiomer purity via peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Measures trace elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual BOC Reagents | GC-MS | Identifies and quantifies residual di-tert-butyl dicarbonate (Boc2O) and tert-butanol by gas chromatography-mass spectrometry. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., de-Boc analogs, diastereomers) using gradient HPLC with UV detection. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using a polarimeter to confirm chiral integrity and batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition as a physical identity and purity indicator. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution using Mie scattering theory applied to laser diffraction data. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures pH of a defined suspension in water to assess acidic/basic degradation products or residual reagents. |
| Loss on Drying | Gravimetric Thermogravimetry | Determines volatile content by measuring weight loss after controlled heating under specified time/temperature/vacuum conditions. |
Technical Specifications of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | +15.0 to +17.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
Safety Information of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID
Industrial (R)-1-N-BOC-4-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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