1,1-Dioxo-tetrahydro-thiopyran-4-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 17396-35-9 |
| Product name | 1,1-Dioxo-tetrahydro-thiopyran-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1,1-Dioxo-tetrahydro-thiopyran-4-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1,1-Dioxo-tetrahydro-thiopyran-4-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1,1-Dioxo-tetrahydro-thiopyran-4-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antifungal agent terbinafine | Preparation of (S)-tetrahydrothiopyran-4-one via asymmetric reduction or chiral resolution, followed by multi-step reactions—including amination and alkylation—to construct the terbinafine molecular scaffold |
| Agrochemical Intermediates | Used in the synthesis of novel sulfur-containing heterocyclic fungicides and insecticides | Employed as a thioether/sulfoxide functionalization building block in nucleophilic substitution or cycloaddition reactions to introduce the thiopyranone core, thereby enhancing biological activity and metabolic stability |
| Fine Fragrances & Chemicals | Used as a stabilizer and synergist in fragrance formulations to improve the volatility persistence of aldehyde- and ester-based aroma compounds | Applied as a controlled-release carrier in fragrance compounding; the weakly polar thiopyran ring forms reversible intermolecular interactions with fragrance molecules to modulate release rate |
Manufacturing Quality Control of 1,1-Dioxo-tetrahydro-thiopyran-4-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component by separation on capillary column and flame ionization detection relative to internal/external standard. |
| Water Content | Karl Fischer Titration | Determines water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol medium. |
| Acidity (as Acetic Acid) | Acid-Base Titration with NaOH | Measures acidic impurities by titration with standardized sodium hydroxide using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Evaluates non-volatile inorganic residue after controlled high-temperature ashing and weighing. |
| Color | Visual Comparison Against APHA Scale | Assesses color intensity by matching sample solution against platinum-cobalt standard solutions. |
| Density at 20 C | Digital Density Meter | Determines mass per unit volume using oscillating U-tube principle calibrated with air and water. |
| Refractive Index at 20 C | Refractometry | Measures bending of light through liquid sample at specified temperature using Abbe refractometer. |
| Heavy Metals (as Pb) | ICP-OES | Quantifies total heavy metals after acid digestion by optical emission detection of characteristic atomic lines. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects and quantifies volatile organic solvents by equilibrium partitioning into headspace followed by GC analysis. |
| Aldehyde Impurities | UV-Vis Spectrophotometry | Measures aldehyde content via formation of colored hydrazone complex with DNPH reagent and absorbance at ~450 nm. |
| Non-Volatile Residue | Evaporation and Gravimetry | Determines residue after gentle evaporation of fixed sample volume under nitrogen and drying to constant weight. |
Technical Specifications of 1,1-Dioxo-tetrahydro-thiopyran-4-one
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1,1-Dioxo-tetrahydro-thiopyran-4-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1,1-Dioxo-tetrahydro-thiopyran-4-one
Safety Information of 1,1-Dioxo-tetrahydro-thiopyran-4-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1,1-Dioxo-tetrahydro-thiopyran-4-one
Industrial 1,1-Dioxo-tetrahydro-thiopyran-4-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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