18-Crown-6 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 17455-13-9 |
| Product name | 18-Crown-6 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 18-Crown-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 18-Crown-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 18-Crown-6
| Industry | Application | Process Description |
|---|---|---|
| Chemical Synthesis | Phase-transfer catalyst | Applied to facilitate reactions between aqueous and organic phases, such as alkylation and redox reactions |
| Pharmaceutical Industry | Drug synthesis intermediate | Used as a key intermediate or chiral control reagent in the synthesis of certain drug molecules |
| Analytical Chemistry | Ion recognition and detection | Employed in colorimetric or fluorescent probe systems for selective recognition and detection of alkali metal ions (e.g., K⁺, Na⁺) |
| Materials Science | Functional material preparation | Integrated as a functional unit in constructing supramolecular architectures or ion-responsive polymers |
| Biochemistry | Enzyme reaction modulation | Applied to modulate the activity of ion-dependent enzymes by complexing specific metal ions, thereby influencing reaction kinetics |
| Electrochemistry | Ion-selective electrodes | Incorporated as a component of electrode membranes to enhance selectivity and response sensitivity toward specific cations |
| Environmental Science | Heavy metal ion removal | Utilized in designing adsorbents or extractants for selective complexation of heavy metal ions |
| Agrochemical Industry | Chiral agrochemical synthesis | Applied as a chiral ligand or auxiliary in asymmetric synthesis to improve enantioselectivity of the product |
Manufacturing Quality Control of 18-Crown-6
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities. Pure 18-crown-6 is typically a white crystalline powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC (e.g., C18 column) with methanol/water or acetonitrile/water as mobile phase, using a UV detector (210–230 nm) to measure the main peak area for purity calculation. |
| Assay | Gas Chromatography (GC) or HPLC | GC is suitable for volatile samples, using an FID detector; HPLC is more commonly used, quantifying the main component via external standard or normalization methods. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using an automatic or capillary melting point apparatus. The standard melting point of 18-crown-6 is approximately 97–102 °C. |
| Moisture Content | Karl Fischer Titration | Accurately determine moisture content in the sample. Coulometric method (for trace water) and volumetric method (for higher water content) are available, suitable for quality control of moisture-sensitive materials. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, dichloromethane) according to ICH guidelines, using headspace sampling with GC/FID analysis. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual heavy metal elements such as lead, mercury, cadmium, and arsenic. Samples require digestion prior to analysis to meet pharmacopeial or chemical safety standards. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H NMR and ¹³C NMR to confirm molecular structure by comparing characteristic peaks with reference spectra to verify structural accuracy. |
| Infrared Absorption Characteristics | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain infrared spectra by pressing pellets or using an ATR accessory, then compare with standard spectra to confirm the presence of functional groups (e.g., C-O-C ether linkages in crown ethers). |
| Thermal Stability | Differential Scanning Calorimetry (DSC) or Thermogravimetric Analysis (TGA) | DSC analyzes melting behavior and polymorphic transitions; TGA measures decomposition temperature and mass loss during heating to evaluate thermal stability. |
Technical Specifications of 18-Crown-6
| Test Item | Specification |
|---|---|
| Appearance | White or colorless to almost white crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 37.0–41.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 18-Crown-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 18-Crown-6
Packaging of 18-Crown-6
Industrial 18-Crown-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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