China Factory Direct
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| CAS number | 174603-56-6 |
| Product name | 4-BROMO-6-FLUOROINDAN-1-ONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing kinase inhibitor–based anticancer drugs (e.g., BTK inhibitors) | Used to construct fluorinated heterocyclic structures via Suzuki coupling or amination reactions |
| Pesticide R&D | Structural modification unit for novel fluorinated insecticides and herbicides | Applied to introduce fluorine and bromine atoms to optimize molecular lipophilicity and target binding activity |
| Organic Synthesis | Multifunctional aryl haloketone building block for constructing complex polycyclic compounds | Employed in the preparation of indane derivatives via Grignard reaction, Wittig reaction, or transition metal–catalyzed cyclization |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at ~254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separates and detects impurities (e.g., regioisomers, dehalogenated by-products) using gradient elution; identification/quantification via retention time and/or mass spectral matching. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., DCM, THF, toluene) using headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water content via electrochemical iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Pb) after acid digestion, using isotopic detection with high sensitivity and multi-element capability. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing (500–600 °C) and precise weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary method per USP <741>. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separates and quantifies chloride ions after sample dissolution and dilution, based on anion exchange and conductivity response. |
| Optical Rotation | Polarimetry | Measures specific rotation at specified wavelength (e.g., 589 nm) and temperature to assess chiral integrity (if applicable to enantiopure batches). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 112–116°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.