2-Fluoro-3-hydroxypyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 174669-74-0 |
| Product name | 2-Fluoro-3-hydroxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-3-hydroxypyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-3-hydroxypyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-3-hydroxypyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate for synthesizing fluoroquinolone antibiotics (e.g., garenoxacin) | Reacted with halogenating reagents (e.g., thionyl chloride) to prepare 2-fluoro-3-chloropyridine, followed by amination, cyclization, and other sequential steps to construct the quinolone core |
| Pesticides | Key structural motif in novel insecticides and fungicides | Used as a heterocyclic building block in coupling reactions (e.g., Suzuki or Heck coupling) to construct fluorinated pyridine-based active molecules |
| Materials Science | Synthetic precursor for hole-transport materials in organic light-emitting diodes (OLEDs) | Subjected to lithium–halogen exchange, then condensed with aldehydes to introduce hydroxyl-functionalized conjugated side chains, thereby tuning the HOMO energy level |
Manufacturing Quality Control of 2-Fluoro-3-hydroxypyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities based on retention time and relative response factors using gradient elution. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatographic separation with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water via iodine-sulfur dioxide reaction in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Residue mass measurement after incineration at 700-800 C following sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary tube method. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light through a solution in specified solvent and path length. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile residue after heating to constant weight at 600 C in a platinum crucible. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity determination using calibrated glass electrode and reference electrode in saturated aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Size analysis based on angular dependence of laser light scattering intensity from dispersed particles in liquid medium. |
Technical Specifications of 2-Fluoro-3-hydroxypyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-3-hydroxypyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-3-hydroxypyridine
Packaging of 2-Fluoro-3-hydroxypyridine
Industrial 2-Fluoro-3-hydroxypyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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