4-Bromo-2-trifluoromethoxyaniline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 175278-09-8 |
| Product name | 4-Bromo-2-trifluoromethoxyaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-2-trifluoromethoxyaniline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-2-trifluoromethoxyaniline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-2-trifluoromethoxyaniline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., BTK inhibitors) | Constructs heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions (e.g., Suzuki or Heck coupling) |
| Agrochemicals | Used to prepare novel insecticides and fungicides containing a trifluormethoxy group | Introduces additional functional groups via diazotization-iodination or Sandmeyer reactions, followed by condensation with heterocyclic compounds |
| Materials Science | Structural unit for hole-transport materials in organic light-emitting diodes (OLEDs) | Couples conjugated moieties (e.g., carbazole, triphenylamine) via Ullmann coupling or Buchwald–Hartwig amination |
Manufacturing Quality Control of 4-Bromo-2-trifluoromethoxyaniline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or UPLC-MS | Separation and identification of impurities (e.g., isomers, dehalogenated by-products, residual starting materials) via chromatographic resolution and spectral/ mass confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., toluene, methanol, THF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, achieving sub-pptr detection limits. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions derived from hydrolysis or synthesis residues. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using controlled heating and optical observation per USP <741>. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing (500–600 °C) and weighing. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline powder) and color intensity compared to platinum-cobalt standards. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm chiral purity (though compound is achiral, used to detect chiral contaminants). |
Technical Specifications of 4-Bromo-2-trifluoromethoxyaniline
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 65–69°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-2-trifluoromethoxyaniline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-2-trifluoromethoxyaniline
Safety Information of 4-Bromo-2-trifluoromethoxyaniline
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Bromo-2-trifluoromethoxyaniline
Industrial 4-Bromo-2-trifluoromethoxyaniline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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