4''-CHLORO-2''-FLUOROACETOPHENONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 175711-83-8 |
| Product name | 4''-CHLORO-2''-FLUOROACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4''-CHLORO-2''-FLUOROACETOPHENONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4''-CHLORO-2''-FLUOROACETOPHENONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4''-CHLORO-2''-FLUOROACETOPHENONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Used in the synthesis of novel oxazolidinone-based antibacterial agents (e.g., linezolid analogues) and other fluorinated drug molecules. |
| Agrochemicals | Agrochemical Intermediate | Serves as a fluorinated aromatic building block for synthesizing herbicidal or insecticidal active ingredients with high efficacy and low toxicity. |
| Organic Synthesis | Structural Building Block | Enables construction of complex organic molecular frameworks via nucleophilic substitution, reduction, or coupling reactions, leveraging the reactivity of fluorine and chlorine substituents and the acetyl group on the benzene ring. |
| Research & Development | Laboratory Reagent | Employed as a reference standard or reaction substrate in early-stage drug screening and new drug development for biological activity assessment and synthetic route exploration. |
Manufacturing Quality Control of 4''-CHLORO-2''-FLUOROACETOPHENONE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and state (usually white to off-white crystalline powder) of the sample under natural light or a standard light source to determine if it meets the specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Compare the sample's infrared absorption spectrum with the reference spectrum. - HPLC: Qualitative analysis by comparing retention time with that of the reference standard. - ¹H NMR: Analyze characteristic chemical shifts and peak shapes to confirm the molecular structure. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column, with methanol-water or acetonitrile-water as the mobile phase. Detect using a UV detector (e.g., 254 nm). Calculate the content of the main component using an external standard method; typically requires ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use a gradient or isocratic elution program to separate and quantify potential impurities (such as starting materials, by-products, degradation products). A single impurity should not exceed 0.5%, and total impurities should not exceed 1.0%. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detector to detect organic solvents possibly remaining from the synthesis process (e.g., toluene, dichloromethane, ethanol), in compliance with ICH Q3C limits. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry at 105°C until constant weight is achieved to measure mass loss, evaluating water and volatile matter content. Typically requires ≤0.5%. |
| Melting Point | Capillary Melting Point Determination | Measure the melting temperature range of the sample using a melting point apparatus (for example, typical melting point of 4'-chloro-2'-fluorobenzyl acetone is about 50–54°C), used to assess purity and consistency. |
| Water Content | Karl Fischer Titration | Determine water content using volumetric or coulometric Karl Fischer titration. Typically requires ≤0.5%. |
Technical Specifications of 4''-CHLORO-2''-FLUOROACETOPHENONE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 45–49°C |
| Refractive Index (n20/D) | 1.542–1.546 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4''-CHLORO-2''-FLUOROACETOPHENONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4''-CHLORO-2''-FLUOROACETOPHENONE
Safety Information of 4''-CHLORO-2''-FLUOROACETOPHENONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4''-CHLORO-2''-FLUOROACETOPHENONE
Industrial 4''-CHLORO-2''-FLUOROACETOPHENONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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