5-Chloroisatin Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 17630-76-1 |
| Product name | 5-Chloroisatin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 5-Chloroisatin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloroisatin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloroisatin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic pharmaceutical intermediate for preparing antitumor and antiviral agents | Chlorination of isatin to introduce a chlorine atom at the 5-position, yielding 5-chloroisatin, followed by subsequent coupling or reduction reactions |
| Agrochemicals | Used in synthesizing certain heterocyclic agrochemical intermediates | Construction of agrochemically active structures via acylation, condensation, and other reactions starting from 5-chloroisatin |
| Dyes | Employed as a high-performance dye intermediate for synthesizing dyes with specific hues and stability | Azo coupling with aromatic amines to produce azo dyes |
| Organic Synthesis | Served as a versatile organic synthesis intermediate for constructing complex molecular frameworks | Expanded application scope through nucleophilic substitution, redox, and cyclization reaction pathways |
Manufacturing Quality Control of 5-Chloroisatin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 5-chloroisatin content by UV detection after chromatographic separation using a reversed-phase C18 column. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isatin, chlorinated by-products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., DMF, toluene, methanol) using gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water. |
| Heavy Metals | ICP-OES | Quantifies total heavy metal content (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after anion-exchange chromatography. |
| Melting Point | Capillary Melting Point Apparatus | Determines the temperature range at which solid 5-chloroisatin transitions to liquid, indicating purity and identity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white-light illumination against standard references. |
| Loss on Drying | Gravimetric Analysis | Measures mass loss after drying under specified temperature and vacuum conditions to determine volatile content. |
| Residue on Ignition | Sulfated Ash Method | Quantifies non-volatile inorganic residue remaining after high-temperature ignition in a muffle furnace. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Bulk Density | Tap Density Measurement | Determines mass per unit volume after controlled tapping of a known powder mass in a graduated cylinder. |
Technical Specifications of 5-Chloroisatin
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 215–219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 5-Chloroisatin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Chloroisatin
Packaging of 5-Chloroisatin
Industrial 5-Chloroisatin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply