N-Fmoc-L-threonol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 176380-53-3 |
| Product name | N-Fmoc-L-threonol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Fmoc-L-threonol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Fmoc-L-threonol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Fmoc-L-threonol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral synthon for synthesizing intermediates of antiviral or antitumor drugs | Protecting group strategy in organic synthesis; the Fmoc group provides amino protection in solid-phase peptide synthesis, facilitating subsequent coupling reactions |
| Peptide Synthesis | Used as a precursor for non-natural amino acids or diol-based structural units | Fmoc-based solid-phase peptide synthesis (Fmoc-SPPS), constructing the target peptide chain via iterative deprotection-coupling cycles |
| Biochemical Research | Used to construct functionalized molecular probes containing a 1,3-butanediol scaffold | Selective functionalization of the Fmoc-protected amino group, followed by deprotection to introduce fluorescent or biologically active moieties |
| Fine Chemicals | Used as a building block for synthesizing chiral ligands or catalysts | Differential protection and activation of hydroxyl and amino groups to participate in asymmetric catalytic system construction |
Manufacturing Quality Control of N-Fmoc-L-threonol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, THF, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detection at sub-pptr levels per USP <232> and <233>. |
| Residual Palladium | ICP-MS | Specific quantification of Pd from catalytic hydrogenation steps using isotope-dilution ICP-MS for high sensitivity and accuracy. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with standardized calibration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Loss on Drying | Gravimetric Thermogravimetry | Weight loss measurement after drying at 60 C under vacuum for 2 hours, indicating volatile content and residual moisture. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution using laser scattering principles and Mie theory for compliance with processing specifications. |
Technical Specifications of N-Fmoc-L-threonol
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Fmoc-L-threonol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Fmoc-L-threonol
Packaging of N-Fmoc-L-threonol
Industrial N-Fmoc-L-threonol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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