China Factory Direct
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| CAS number | 1765-93-1 |
| Product name | 4-Fluorobenzeneboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthesis of active pharmaceutical ingredients (APIs), including antidiabetic, anti-inflammatory, and antitumor agents | Suzuki-Miyaura cross-coupling (used as an arylboron reagent to couple with organic halides for carbon–carbon bond formation) |
| Agrochemicals | Preparation of fluorinated agrochemical intermediates for synthesizing novel insecticides and herbicides | Cross-coupling reactions to introduce fluorophenyl groups, enhancing lipophilicity and metabolic stability of agrochemicals |
| Advanced Materials & OLED | Synthesis of organic electroluminescent (OLED) materials and organic semiconductor materials | Exploiting boronic acid reactivity to construct conjugated organic molecular frameworks, improving optoelectronic performance |
| Organic Synthesis | Serving as an organic synthesis intermediate for constructing complex fluorinated aromatic compounds | Catalyzed cross-coupling, functional group transformations (e.g., conversion to phenols or halides), and mechanistic studies |
| Analytical Chemistry | Used as a derivatization reagent for analytical detection | Reacting with specific analytes to generate detectable derivatives for chromatographic or spectroscopic analysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 4-fluorophenylboronic acid peak area against a calibrated standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separates and quantifies impurities (e.g., 4-fluoroaniline, biphenyl derivatives) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water mass fraction via coulometric or volumetric titration using iodine generation in pyridine/methanol-based reagent. |
| Heavy Metals (as Pb) | ICP-OES | Measures total heavy metal content (Pb, Cd, Ni, etc.) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity. |
| Loss on Drying | Gravimetric Analysis | Measures mass loss after drying under controlled temperature/vacuum, reflecting volatile and moisture content. |
| Residue on Ignition | Weight Loss on Ignition | Quantifies inorganic ash content after high-temperature incineration of sample followed by gravimetric measurement. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using angular scattering pattern of laser light. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of saturated aqueous suspension using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral purity (though compound is achiral, used for batch consistency verification). |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.