2-AMINO-5-BROMO-3-METHOXYBENZONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 176718-54-0 |
| Product name | 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing kinase inhibitor–based anticancer drugs (e.g., BRAF inhibitors) | Constructs benzimidazole or indole scaffolds via palladium-catalyzed cross-coupling reactions (e.g., Suzuki or Heck coupling) |
| Agrochemical Intermediates | Used in the preparation of novel brominated benzonitrile-based insecticides and fungicides | Introduces functional groups through multistep reactions including nitration, reduction, diazotization, and substitution |
| Materials Science | Structural unit for hole-transport materials in organic light-emitting diodes (OLEDs) | Couples carbazole or triarylamine moieties via Ullmann coupling or Buchwald–Hartwig amination |
Manufacturing Quality Control of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection Method | Observe the color, state, and presence of foreign matter under natural light or standard lighting. Typically appears as a white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Measure the infrared absorption spectrum and compare it with reference spectra to identify characteristic functional group absorption peaks (e.g., cyano, amino, aromatic rings). - HPLC: Retention time should match the reference standard under specific chromatographic conditions. - ¹H NMR: Confirm molecular structure characteristics by chemical shift, integration area, and coupling constants. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect using a UV detector (typically around 254 nm) and calculate the main component content via external standard method. Purity requirement is usually ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main compound from potential impurities (e.g., starting materials, intermediates, by-products, degradation products) using gradient or isocratic elution programs. Control individual and total impurity limits using area normalization or correction factor methods (e.g., single impurity ≤0.5%, total impurities ≤1.0%). |
| Moisture | Karl Fischer Titration | Determine moisture content using Karl Fischer reagent that reacts quantitatively with water in the sample. Use coulometric or volumetric titration methods. Typically requires ≤0.5% moisture. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with an FID detector. Test for residual organic solvents (e.g., toluene, dichloromethane, ethanol) according to ICH Q3C guidelines and ensure they are within safe limits. |
| Melting Point | Capillary Melting Point Determination | Load the sample into a melting point capillary and heat at a specified rate in a melting point apparatus. Record the initial to final melting temperature range and compare with literature values (e.g., approximately 160–164°C) to assess purity. |
| Ignition Residue/ Ash Content | Gravimetric Method | Weigh the inorganic residue after high-temperature incineration of the sample to evaluate inorganic impurity content. Typically requires ≤0.1%. |
Technical Specifications of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142.0 - 146.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
Safety Information of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE
Industrial 2-AMINO-5-BROMO-3-METHOXYBENZONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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