1,4-Dioxa-8-azaspiro[4.5]decane Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 177-11-7 |
| Product name | 1,4-Dioxa-8-azaspiro[4.5]decane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1,4-Dioxa-8-azaspiro[4.5]decane
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1,4-Dioxa-8-azaspiro[4.5]decane Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1,4-Dioxa-8-azaspiro[4.5]decane
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of opioid analgesics (e.g., pethidine, fentanyl derivatives) | Used to construct piperidine-ring-containing drug molecules via organic synthesis reactions, including reductive amination, alkylation, or acylation |
| Pesticides | Intermediate for synthesizing bioactive nitrogen-containing heterocyclic compounds, such as insecticides or herbicides | Applied in nucleophilic substitution or condensation reactions to introduce functional groups and build the target pesticide molecular scaffold |
| Fine Chemicals | Preparation of other piperidine derivatives and functionalized heterocyclic compounds | Employed as a protected form of 4-piperidone, enabling participation in multi-step syntheses after deprotection under mild conditions |
Manufacturing Quality Control of 1,4-Dioxa-8-azaspiro[4.5]decane
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, physical state (e.g., colorless to pale yellow liquid), clarity, etc., to determine compliance with specified requirements. |
| Identification | Infrared Spectroscopy (IR) | Confirm compound structure based on characteristic absorption peaks in the infrared spectrum (e.g., C–O–C acetal structure around 1100 cm⁻¹, N–H around 3300 cm⁻¹, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Confirm structural features based on characteristic chemical shifts (e.g., acetal protons at δ ≈ 4.8–5.0 ppm, piperidine ring protons at δ ≈ 1.5–3.5 ppm). | |
| Content Determination | Gas Chromatography (GC) | Separate components using a capillary column and quantify with a Flame Ionization Detector (FID); calculate main component content using internal standard method or area normalization. |
| High-Performance Liquid Chromatography (HPLC) | Applicable for thermally unstable or high-boiling samples; use C18 reversed-phase column with UV detector (e.g., 210 nm) for quantitative analysis. | |
| Related Substances (Impurities) | GC or HPLC | Use the same method as for content determination; assess individual and total impurity levels by comparing peak areas with reference standards or self-reference methods, ensuring compliance with specified limits. |
| Moisture Content | Karl Fischer Titration | Determine water content using potentiometric or coulometric Karl Fischer titration, ensuring compliance with drying loss or moisture limit requirements. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detect organic solvents potentially remaining from synthesis (e.g., toluene, ethanol, dichloromethane), in accordance with ICH Q3C guidelines. |
| pH (if applicable, for solutions) | pH Meter Method | Prepare the sample as a solution at the specified concentration, then measure pH using a calibrated pH meter. |
| Optical Rotation (if applicable) | Polarimeter Method | If the compound is chiral or exists as optical isomers, measure specific rotation to control stereochemical purity. |
Technical Specifications of 1,4-Dioxa-8-azaspiro[4.5]decane
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78.0–82.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1,4-Dioxa-8-azaspiro[4.5]decane
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1,4-Dioxa-8-azaspiro[4.5]decane
Safety Information of 1,4-Dioxa-8-azaspiro[4.5]decane
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1,4-Dioxa-8-azaspiro[4.5]decane
Industrial 1,4-Dioxa-8-azaspiro[4.5]decane Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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