China Factory Direct
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| CAS number | 177211-26-6 |
| Product name | 4'-CHLORO-2'-FLUORO-5'-METHYLACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing novel herbicides (e.g., triazolinone herbicides) | Participates in constructing the active molecular core via reductive amination, cyclization, and related steps |
| Pharmaceuticals | Structural building block for fluorinated, chlorinated heterocyclic anticancer and anti-inflammatory drug candidates | Introduced as an aryl ketone moiety and further modified via Wittig reaction, hydrazone formation, or metal-catalyzed coupling |
| Materials Science | Functionalized precursor for liquid crystal monomers and organic light-emitting diode (OLED) materials | Integrated into rigid fluorinated liquid crystal backbones or hole-transporting groups via halogen exchange or coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., isomers, dehalogenated, oxidized, or hydrolyzed by-products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, dichloromethane, methanol) based on calibrated retention times and peak areas. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, using isotopic detection for sub-ppq sensitivity and compliance with ICH Q3D limits. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration with silver nitrate endpoint detection for inorganic chloride impurities. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 700–800 °C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating; deviation from literature value (e.g., 68–70 °C) indicates impurity or polymorphic variation. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral contamination (though compound is achiral, confirms absence of optically active impurities). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to assess crystallinity and handling suitability per processing requirements. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 78-82°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.