Benzyl N-Boc-4-piperidinecarboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 177990-33-9 |
| Product name | Benzyl N-Boc-4-piperidinecarboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Benzyl N-Boc-4-piperidinecarboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Benzyl N-Boc-4-piperidinecarboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Benzyl N-Boc-4-piperidinecarboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of piperidine-containing drug molecules, such as antihistamines, analgesics, or precursors to psychotropic agents | Employed as a protecting group in multistep organic synthesis; target functional groups are introduced following selective Boc and/or benzyl deprotection |
| Organic Synthesis Reagents | Key building block for constructing 4-substituted piperidine scaffolds | Enables functional group transformation via selective Boc or benzyl ester removal under palladium-catalyzed hydrogenation or acidic conditions |
| Drug Discovery | Structural modification module for high-throughput screening (HTS) or structure–activity relationship (SAR) studies | Derivatized via amidation, reduction, or coupling reactions to generate diverse compound libraries |
Manufacturing Quality Control of Benzyl N-Boc-4-piperidinecarboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., toluene, THF, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Inductively coupled plasma optical emission spectrometry for simultaneous multi-element quantification of heavy metals (e.g., Pb, Cd, Ni, Fe) after acid digestion. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection, referenced to sodium chloride standards. |
| Residual Palladium | ICP-MS | Inductively coupled plasma mass spectrometry for ultra-trace palladium detection following microwave-assisted acid digestion. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Weight loss measured after drying under controlled temperature and vacuum, reflecting volatile content and moisture. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory and calibrated optical model. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic mesophilic microorganisms via filtration, membrane transfer to agar media, and incubation per USP <61>. |
Technical Specifications of Benzyl N-Boc-4-piperidinecarboxylate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Benzyl N-Boc-4-piperidinecarboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Benzyl N-Boc-4-piperidinecarboxylate
Safety Information of Benzyl N-Boc-4-piperidinecarboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Benzyl N-Boc-4-piperidinecarboxylate
Industrial Benzyl N-Boc-4-piperidinecarboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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