4-Bromo-5-methyl-1H-pyrazol-3-amine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1780-72-9 |
| Product name | 4-Bromo-5-methyl-1H-pyrazol-3-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-5-methyl-1H-pyrazol-3-amine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-5-methyl-1H-pyrazol-3-amine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-5-methyl-1H-pyrazol-3-amine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor and antiviral active compounds | Applied in organic synthesis and catalytic reactions |
| Pesticides | Used as an intermediate in the synthesis of high-efficiency insecticides or fungicides | Applied in halogenation and condensation reactions |
| Dyes | Used in the preparation of pyrazole-based dyes or pigments to enhance color fastness and stability | Applied in diazotization and coupling reactions |
| Materials Science | Used as a ligand in the synthesis of functional polymeric materials or coordination compounds | Applied in polymerization and complexation reactions |
| Research Reagents | Used as an organic synthesis building block for structural modification of complex molecules or development of novel compounds | Applied in multistep synthesis and purification processes |
Manufacturing Quality Control of 4-Bromo-5-methyl-1H-pyrazol-3-amine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection + Physical Property Measurement | Observe sample color and physical state (typically white to pale yellow crystalline powder); determine melting point range (literature value: approximately 130–135°C), in accordance with pharmacopoeial or internal corporate standards. |
| Assay (Active Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with mobile phases such as water-acetonitrile or methanol-buffer salt (e.g., phosphate); detect using a UV detector (220–254 nm); quantify via external standard method to ensure active ingredient purity ≥98.0%. |
| Impurity Profile Analysis | HPLC-UV / HPLC-MS | Employ gradient elution to separate potential impurities (e.g., unreacted starting materials, debrominated by-products, oxidation products); identify impurities by comparing retention times with reference standards or via mass spectrometry structural confirmation; control single impurity ≤0.5%, total impurities ≤1.0%. |
| Bromine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion-Selective Electrode | Convert sample bromine to bromide ions via oxygen bomb combustion, absorb in water, then quantify Br⁻ concentration using ion chromatography or an ion-selective electrode; verify theoretical bromine content (theoretical value ~39.2%). |
| Water Content | Karl Fischer Titration | Determine trace water content using coulometric or volumetric Karl Fischer methods; control water content ≤0.5% (to prevent hydrolysis or crystalline water effects on stability). |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents potentially present during synthesis (e.g., DMF, ethanol, ethyl acetate) using headspace or direct injection with FID detection; comply with ICH Q3C limits. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure heavy metal levels (e.g., lead, cadmium, mercury, arsenic); comply with pharmacopoeial limits (e.g., Pb ≤5 ppm). |
| Particle Size Distribution (if applicable) | Laser Diffraction / Microscopy | For powdered raw materials, determine particle size distribution to ensure process consistency (e.g., D90 <50 μm), impacting solubility and formulation uniformity. |
| Solubility and pH (Solution) | Solubility Determination + pH Meter | Determine solubility in solvents such as water, ethanol, and DMSO; measure pH of saturated solution (typically slightly acidic to neutral, pH 5–7) to assess stability. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare characteristic absorption peaks with reference spectra (e.g., N–H stretch ~3400 cm⁻¹, C=N ~1600 cm⁻¹, C–Br ~500–600 cm⁻¹) to confirm structural consistency. |
| Nuclear Magnetic Resonance (1H NMR / 13C NMR) | Nuclear Magnetic Resonance Spectroscopy | Perform measurements in DMSO-d₆ or CDCl₃; compare proton and carbon chemical shifts and integration ratios to confirm molecular structure and absence of structural isomers (e.g., N-substituted isomers). |
Technical Specifications of 4-Bromo-5-methyl-1H-pyrazol-3-amine
| Test Item | Specification |
|---|---|
| Appearance | Red solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-5-methyl-1H-pyrazol-3-amine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-5-methyl-1H-pyrazol-3-amine
Safety Information of 4-Bromo-5-methyl-1H-pyrazol-3-amine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Bromo-5-methyl-1H-pyrazol-3-amine
Industrial 4-Bromo-5-methyl-1H-pyrazol-3-amine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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