China Factory Direct
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| CAS number | 178305-99-2 |
| Product name | 2-Fluoro-4-biphenylylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), used in the preparation of anticancer, antiviral, and central nervous system drugs | Applied in Suzuki-Miyaura coupling reactions |
| Agrochemicals | Synthesis of novel bioactive pesticide molecules, such as herbicides and insecticides | Applied in palladium-catalyzed cross-coupling reactions |
| Materials Science | Preparation of functional materials for organic light-emitting diodes (OLEDs) or liquid crystal molecules | Applied in Suzuki coupling to construct conjugated structures |
| Fine Chemicals | Boronic acid-based synthon for constructing complex aromatic frameworks | Applied in arylations during multistep organic synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., unreacted intermediates, isomers, de-boronated products) via gradient HPLC-UV with system suitability criteria. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Cu) after acid digestion using inductively coupled plasma mass spectrometry with isotopic detection. |
| Residual Palladium | ICP-OES | Measures palladium from Suzuki coupling catalyst residue via microwave-assisted acid digestion followed by plasma optical emission detection. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying at specified temperature (e.g., 105 C) for fixed duration under vacuum or nitrogen. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions leached from residual reagents using suppressed conductivity detection with carbonate/bicarbonate eluent. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of dry powder using Mie theory-based light scattering analysis with dispersion in air or inert gas. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.